Clinical Trial Posts

NONSEDA Official title: Non-sedation versus sedation with a daily wake-up trial in critically ill patients receiving mechanical ventilation. The NONSEDA-trial. An investigator-initiated, randomised, clinical, parallel-group, multinational, superiority trialTrial start year: 2014 Trial websiteClick below to view websiteView website Trial registrationNCT01967680View registration Design paper2014Non-sedation versus sedation with a daily wake-up trial in critically ill patients receiving …

NONSEDA – Non-sedation versus sedation with a daily wake-up trial in critically ill patients receiving mechanical ventilation. The NONSEDA-trial. An investigator-initiated, randomised, clinical, parallel-group, multinational, superiority trial. Start year: 2014 Read More »

Hyperalgesi 1 Official title: Characterization of Secondary Hyperalgesia in Healthy VolunteersTrial start year: 2014 Trial websiteNo website available Trial registrationNCT02166164View registration Design paperNo design paper published Result paper2016The Area of Secondary Hyperalgesia following Heat Stimulation in Healthy Male Volunteers: Inter- and Intra-Individual Variance and ReproducibilityDownload full paper

Sheppheart-CABG RCT Official title: A randomised clinical trial of a comprehensive physical and psycho-educative rehabilitation programme plus usual care versus usual care in phase 1 rehabilitation after coronary artery bypass graftingTrial start year: 2014 Trial websiteNo website available Trial registrationNCT02290262View registration Design paper2017SheppHeartCABG trial—comprehensive early rehabilitation after coronary artery bypass grafting: a protocol for a …

Sheppheart-CABG RCT – A randomised clinical trial of a comprehensive physical and psycho-educative rehabilitation programme plus usual care versus usual care in phase 1 rehabilitation after coronary artery bypass grafting. Start year: 2014 Read More »

RESPECT (CIRE) Official title: Rehabilitation including social and physical activity in children and teenagers with cancerTrial start year: 2013 Trial websiteNo website available Trial registrationNCT01772862View registration Design paper2013Study protocol: rehabilitation including social and physical activity and education in children and teenagers with cancer (RESPECT)Download full paper Result paper2016Cardiorespiratory fitness and physical function in children with …

RESPECT (CIRE) – Rehabilitation including social and physical activity in children and teenagers with cancer. Start year: 2013 Read More »

TICH-2 Official title: Tranexamic acid for IntraCerebral Haemorrhage (TICH-2): a pragmatic phase III prospective double-blind randomised placebo-controlled trialTrial start year: 2013 Trial websitewww.tich-2.orgView website Trial registrationISRCTN93732214View registration Design paper2016Intravenous tranexamic acid for hyperacute primary intracerebral hemorrhage: Protocol for a randomized, placebo-controlled trialDownload full paper Result paper2018Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international …

TICH-2 – Tranexamic acid for IntraCerebral Haemorrhage (TICH-2): a pragmatic phase III prospective double-blind randomised placebo-controlled trial . Start year: 2013 Read More »

IMPROvED Official title: Personalized medicine for pregnant women: Novel metabolomic and proteomic biomarkers to detect pre-eclampsia and improve outcomeTrial start year: 2013 Trial websitewww.fp7-improved.euView website Trial registrationNCT01891240View registration Design paper2013A multi-centre phase IIa clinical study of predictive testing for preeclampsia: improved pregnancy outcomes via early detection (IMPROvED)Download full paper Result paperNo result paper published

EuroHYP-1 Official title: European multicentre, randomised, phase III clinical trial of therapeutic hypothermia plus best medical treatment versus best medical treatment alone for acute ischaemic strokeTrial start year: 2013 Trial websiteNo website available Trial registrationNCT01833312View registration Design paper2013EuroHYP-1: European multicenter, randomized, phase III clinical trial of therapeutic hypothermia plus best medical treatment vs. best medical …

EuroHYP-1 – European multicentre, randomised, phase III clinical trial of therapeutic hypothermia plus best medical treatment versus best medical treatment alone for acute ischaemic stroke. Start year: 2013 Read More »

Obanop-trial Official title: ‘In situ simulation’ versus ‘off site simulation’ in obstetric emergencies and their effect on knowledge, safety attitudes, team performance, stress, and motivationTrial start year: 2013 Trial websiteNo website available Trial registrationNCT01792674View registration Design paper2013’In situ simulation’ versus ‘off site simulation’ in obstetric emergencies and their effect on knowledge, safety attitudes, team performance, …

Obanop-trial – ‘In situ simulation’ versus ‘off site simulation’ in obstetric emergencies and their effect on knowledge, safety attitudes, team performance, stress, and motivation. Start year: 2013 Read More »

H11 Official title: Very early FDG-PET/CT-response adapted therapy for advanced stage Hodgkin’s lymphoma, a randomized phase III non-inferiority study of the EORTC Lymphoma Group. Prematurely terminatedTrial start year: 2013 Trial websiteNo website available Trial registrationNCT01652261View registration Design paper2012Very early FDG-PET/CT-response adapted therapy for advanced stage Hodgkin Lymphoma (H11), a randomized phase III non-inferiority study of …

H11 – Very early FDG-PET/CT-response adapted therapy for advanced stage Hodgkin’s lymphoma, a randomized phase III non-inferiority study of the EORTC Lymphoma Group. Prematurely terminated. Start year: 2013 Read More »

SheppHeart-CABG PILOT Official title: Shaping outcomes by exercise training and psycho-education in phase 1 for coronary artery bypass grafting patientsTrial start year: 2013 Trial websiteNo website available Trial registrationNCT01941355View registration Design paperNo design paper published Result paper2015Early physical training and psycho-educational intervention for patients undergoing coronary artery bypass grafting. The SheppHeart randomized 2 × 2 …

SheppHeart-CABG PILOT – Shaping outcomes by exercise training and psycho-education in phase 1 for coronary artery bypass grafting patients. Start year: 2013 Read More »