Update 04-01-2021: CTU offices are partly closed due to the COVID-19 pandemic until further notice. Some of CTU’s staff work at CTU, but we try at the same time to conduct as much work from our homes as possible. You can contact all of us by e-mail or by phone (see Contact).

Welcome to the Copenhagen Trial Unit − The CTU

The CTU is a clinical intervention research unit conducting clinical research within all specialties. We offer flexible collaboration and consulting at all stages of clinical research.

The CTU has been involved in the conduct of more than 151 randomised clinical trials in which more than 132,000 participants were randomised. We provide expertise and infrastructure in planning, conduct, analysis, and interpretation of randomised clinical trials, including development of trial methodology and education.

The CTU has been involved in the conduct of more than 500 protocols for systematic reviews, which has materialised in the publication of more than 300 systematic reviews published within and outside The Cochrane Collaboration. The CTU has developed methodology and software for conducting Trial Sequential Analysis (TSA). We provide advice, support, and full collaboration during the protocol and systematic review development. We offer expertise in search strategy design, conduct literature searches for systematic reviews, and offer help with or conduct of meta-analyses.

The CTU hosts the Editorial Team Office of the Cochrane Hepato-Biliary Group (CHBG) - one of the 56 global Collaborative Review Groups within The Cochrane Collaboration - as well as the Danish Clinical Research Infrastructures Network (DCRIN), the Danish coordinating hub of the Nordic Trial Alliance (NTA), and the Danish coordinating hub of the European Clinical Research Infrastructures Network (ECRIN).

We offer creative collaboration and consulting from concept,
through conduct and to completion.

News

By the 4th of January 2021, the CTU has reached 1,165 publications, and over 3,900 yearly references to its publications. By the same date, the CTU has a h-index of 88. Please see About the CTU, and History of the CTU. Click "View here" to see full publication list of CTU 1995 to present:
View here
Juul S, et al. Interventions for treatment of COVID-19: second edition of a living systematic review with meta-analyses and trial sequential analyses (The LIVING Project). medRxiv preprint. November 24, 2020;1-73.doi: https://doi.org/10.1101/2020.11.22.20236448.
View here
Korang SK, et al. Vaccines to prevent COVID-19: a protocol for a living systematic review with network meta-analysis including individual patient data (The LIVING VACCINE Project). Systematic Reviews. 2020;(9:262):1-15.
View here
Juul S, et al. Interventions for treatment of COVID-19: A living systematic review with meta-analyses and trial sequential analyses (The LIVING Project). PLOS Med 17(9): e1003293. https://doi.org/10.1371/journal. pmed.1003293.
View here
Juul S, et al. Interventions for treatment of COVID-19: a protocol for a living systematic review with network meta-analysis including individual patient data (The LIVING Project). Systematic Reviews. 2020;(9:108):1-12.
View here
Bjerre M, et al. Serum osteoprotegerin as a long-term predictor for patients with stable coronary artery disease and its association with diabetes and statin treatment: A CLARICOR trial 10-year follow-up substudy. Atherosclerosis. May 1, 2020;301:8-14.
View here
Petersen MW, et al. Low-dose hydrocortisone in patients with COVID-19 and severe hypoxia (COVID STEROID) trial-Protocol and statistical analysis plan. Acta Anaesthesiol Scand. July 21, 2020;00:1–11.
View here
Storebø OJ and Gluud C. Methylphenidate for ADHD rejected from the WHO Essential Medicines List due to uncertainties in benefit-harm profile. BMJ Evidence-Based Medicine. April 24, 2020;Online ahead of print.
View here
Wichmann S, et al. Loop diuretics in adult intensive care patients with fluid overload: A protocol for a systematic review of randomised clinical trials with meta-analysis and Trial Sequential Analysis. Acta Anaesthesiol Scand. June 12, 2020;00:1–8.
View here
Simonetti RG, et al. Plasma expanders for people with cirrhosis and large ascites treated with abdominal paracentesis. Cochrane Database Syst Rev. June 28, 2019; 6(6):CD004039.
View here