Details of trials conducted with the involvement of the CTU

Details on trials with involvement of the cTU

Below are all clinical trials the CTU has been involved in. For every trial, a detailed trial page can be accessed by clicking on the trial title. Use the search bar to search for a specific trial name.

Overcome Trial – A Digitally Supported Guided Self-determination Intervention Versus Attention Control for People With Type 2 Diabetes in Outpatient Clinics – a Randomised Clinical Trial. Start year: 2020

AFIB-ICU – The international “New-onset Atrial Fibrillation in the Intensive Care Unit” (AFIB-ICU) Cohorte Study. Start year: 2020

COVID-STEROID 2 Trial – Higher vs. Lower Doses of Dexamethasone in Patients With COVID-19 and Severe Hypoxia. Start year: 2020

HOT-COVID – Handling Oxygenation Targets in COVID-19 Patients With Acute Hypoxaemic Respiratory Failure in the Intensive Care Unit: A Randomised Clinical Trial of a Lower Versus a Higher Oxygenation Target. Start year: 2020

GODIF-ICU – Goal Directed Fluid Removal in Intensive Care Patients With Fluid Overload – A Randomized, Blinded, Placebo-controlled Trial (GODIF). Start year: 2020

TEENS – Treatment Effects of Internet-based Emotion Regulation Individual Therapy for Adolescents (ERITA) Added to Treatment as Usual in Young People With Non-Suicidal Self-Injury – (TEENS) Feasibility Trial. Start year: 2020

SWEET – Sweeteners and Sweetness Enhancers: Prolonged Effects on Health, Obesity and Safety. Start year: 2020

COVID STEROID Trial – Low-dose Hydrocortisone in Patients With COVID-19 and Severe Hypoxia – the COVID STEROID Trial. Prematurely terminated. Start year: 2020

SafeBoosC-III – Safeguarding the Brain of Our Smallest Children – an Investigator-initiated, Pragmatic, Open Label, Multinational Randomized Phase III – clinical Trial Evaluating Treatment Based on Near-infrared Spectroscopy Monitoring Versus Treatment as Usual in Premature Infants. Start year: 2019

RoomLight Trial – Dynamic LED-light Versus Usual Care for Depressed Inpatient: A Randomised Clinical Trial. Start year: 2019

DRAIN – Danish RAndomized Trial of External Ventricular Drainage Cessation IN Aneurysmal Subarachnoid Haemorrhage (DRAIN). Start year: 2019

TENSION – Efficacy and Safety of Thrombectomy in Stroke With Extended Lesion and Extended Time Window: a Randomized, Controlled Trial. Start year: 2018

TECTO – Treatment Effects of Family Based Cognitive Therapy in Children and Adolescents With Obsessive Compulsive Disorder. Start year: 2018

MBT-Trial – Short-term Versus Long-term Mentalization-based Therapy for Outpatients With Subthreshold or Diagnosed Borderline Personality Disorder: a Randomized Clinical Trial. Start year: 2018

VIXIE – Hyperoxia and antioxidants during major non-cardiac surgery and risk of cardiovascular complications, a blinded 2×2 factorial randomised clinical trial. Start year: 2018

AID-ICU – Agents Intervening Against Delirium in Intensive Care Unit (AID-ICU) A Randomized, Blinded, Placebo-controlled Trial. Start year: 2018

MACUSTAR – Development of Novel Clinical Endpoints for Interventional Clinical Trials With a Regulatory and Patient Access Intention in Patients With Intermediate Age-related Macular Degeneration (AMD). Start year: 2018

CLASSIC – The Conservative vs. Liberal Approach to Fluid Therapy of Septic Shock in Intensive Care Trial. Start year: 2018

TIM-TBI – Early mobilisation by head-up tilt with stepping compared with standard care after severe traumatic brain injury – a randomised clinical feasibility trial. Start year: 2017

ROOM-LIGHT Feasibility – Dynamic LED-light as treatment for depressed patients in inpatient wards: A feasibility trial. Start year: 2017

HOT-ICU – Handling oxygenation targets in adults with acute hypoxaemic respiratory failure in the intensive care unit: A randomised clinical trial of a lower versus a higher oxygenation target. Start year: 2017

Good-Ides – An Open-Label Phase II Study in Anti-GBM Disease (Goodpasture’s Disease) With Adverse Renal Prognosis to Evaluate the Efficacy and Safety of IdeS – GOOD-IDES. Start year: 2017

TTM2 – Targeted hypothermia versus targeted normothermia after out-of-hospital cardiac arrest (TTM2) – A randomised clinical trial. Start year: 2017

SIUTIT – The effects of ventilation tubes versus no ventilation tubes for recurrent acute otitis media or chronic otitis media with effusion in 9 to 36 month old greenlandic children – a randomised clinical trial. Prematurely terminated. Start year: 2016

AID-ICU cohort – Agents Intervening against Delirium in Intensive Care Unit (AID-ICU): An international inception cohort study. Start year: 2016

SUP-ICU – Stress Ulcer Prophylaxis in the Intensive Care Unit (SUP-ICU). Start year: 2016

PANSAID – PAracetamol and NSAID in combination: A randomised, blinded, parallel, 4-group clinical trial. Start year: 2015

Hyperalgesi 2 – To Determine the Degree of Association Between Heat Pain Detection Threshold and Area of Secondary Hyperalgesia Following Brief Thermal Sensitization in Healthy Male Volunteers. Start year: 2015

Hyperalgesi 3 – Is the Volume of the Caudate Nuclei Associated With Area of Secondary Hyperalgesia? – A Study of Healthy Volunteers. Start year: 2015

DISCHARGE – Diagnostic imaging strategies for patients with stable chest pain and intermediate risk of coronary artery disease: Comparative effectiveness research of existing technologies) – A pragmatic randomised controlled trial of CT versus ICA. Start year: 2015