The Cochrane Hepato-Biliary Group

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About the CHBG

‍The Editorial Team Office of The Cochrane Hepato-Biliary Group (CHBG) is hosted by the CTU. The CHBG is part of the international Cochrane Network, which consists of evidence synthesis units, thematic, review, and geographic groups.

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The CHBG focuses on the production of high-quality systematic reviews within the hepato-biliary field. We address important research questions for decision-makers, health service providers, consumers, and other individuals. The reviews can be on prevention, diagnosis, prognosis, and treatment and consists of pair-wise comparison systematic reviews, rapid review, prototype reviews, network systematic reviews, overview of reviews of observational studies or randomised clinical trials. Meta-analysis is the base of a systematic review that should be supported by a Trial Sequential Analysis to control random type I and type II errors [1,2,3].

The CHBG Editorial Team staff, helped by international CHBG Editors, provides guidance and assistance to systematic review authors from around the world during the whole or any step of the review process, from title registration of the research question through development of the protocol and review, and to their publication in The Cochrane Database of Systematic Reviews (CDSR) on the Cochrane Library. All Cochrane reviews are peer reviewed. The 2024 five-year Impact Factor for the Cochrane Database of Systematic Reviews is 10.9.

‍We need teams of people eager to work on systematic reviews. If you have a research question that has not been answered in a systematic way or the collected evidence is out of date, you are most welcome to contact us. Information for authors can be found here.

A review team consists of people with interest in evidence-based medicine and research, having various expertise physicians, consumers, statisticians, methodologists, and people with language skills.

The CHBG was registered with The Cochrane Collaboration on 29 of March 1996. Professor, Dr Med Sci Christian Gluud is the founding Coordinating Editor. Since then, more than 2000 people, from about 130 countries, with different backgrounds, have been engaged in the CHBG work answering methodological questions, collecting randomised clinical trials for inclusion in the CHBG Controlled Trials Register, and analysing the evidence included in systematic reviews on diagnosis, prevention, and treatment of hepato-biliary diseases. The CHBG Controlled Trials Register is published in the Cochrane Register of Controlled Trials (CENTRAL), part of The Cochrane Library. CENTRAL is freely available to Cochrane members via the Cochrane Register of Studies Online (CRSO).

    1. Wetterslev J, Thorlund K, Brok J, Gluud C. Trial sequential analysis may establish when firm evidence is reached in cumulative meta-analysis. Journal of Clinical Epidemiology 2008;61(1):64-75. [DOI: 10.1016/j.jclinepi.2007.03.013]

    2. Thorlund K, Devereaux PJ, 3.Wetterslev J, Guyatt G, Ioannidis JP, Thabane L, et al. Can trial sequential monitoring boundaries reduce spurious inferences from meta-analysis? International Journal of Epidemiology 2009;38(1):276-86. [DOI: 10.1093/ije/dyn179]

    3. Wetterslev J, Jakobsen JC, Gluud C. Trial sequential analysis in systematic reviews with meta-analysis. BMC Medical Research Methodology 2017;17(1):1-18. [DOI: 10.1186/s12874-017-0315-7]

Website

Visit the Cochrane Hepato-Biliary Group website for contact and more information