The Cochrane Hepato-Biliary Group

The Copenhagen Trial Unit (CTU) hosts the Editorial Team Office of The Cochrane Hepato-Biliary Group (CHBG), one of the 53 systematic review groups within The Cochrane Collaboration. The CHBG editorial staff works with more than 2000 people all over the world. The roles of these people are either as review authors, peer reviewers, translators, handsearchers, consumers, experts in statistics, editors, or simply members who follow the progress and use the products of the CHBG work. The CHBG editorial team guides authors and works with authors during the preparation of Cochrane systematic reviews, starting with the review title registration, review protocol development, the final preparation of the Cochrane review, and its subsequent updates and publication in The Cochrane Database of Systematic Reviews, part of The Cochrane Library. Cochrane reviews should be updated every two years or as soon as new evidence is published. CHBG authors receive help with the design of search strategies for different literature databases and may receive copies of the publications of relevance to their reviews during the whole review preparation process. For the purpose, The CHBG maintains a CHBG Controlled Trials Register that is published in the Cochrane Register of Controlled Trials (CENTRAL), part of The Cochrane Library. The CHBG conducts systematic reviews of interventions, diagnostic test accuracy, and overview of reviews. There are also different subtypes within the mentioned reviews. All CHBG protocols and reviews undergo extensive peer reviewing, multiple review checks, and editorial approval before publication. In order to reach a broader public, The CHBG encourages also sister publications of CHBG reviews in various journals. However, there are some central Cochrane rules that need to be considered before sending in one’s manuscript to a paper journal.

The work of The CHBG until 2011 has been described in a publication by Klingenberg and co-workers in Journal of Gastroenterology and Hepatology. View. For current status, people are invited to visit The CHBG website.

In December 2017, there were 135 Cochrane protocols for systematic reviews and 207 Cochrane systematic reviews published in The Cochrane Database of Systematic Reviews (The Cochrane Library).

The CHBG editorial staff register people who wish to work with the Group on Archie which is the Cochrane Collaboration's central server for managing documents and contacts details. Review Manager (RevMan) is the Cochrane Collaboration software used for preparing and maintaining Cochrane Reviews.  Archie and RevMan form the Cochrane Information Management System (IMS), designed to enable contributors to the Cochrane Collaboration to produce high quality systematic reviews of the evidence of the effects of healthcare and deliver these for publication in The Cochrane Library.

The CHBG together with the CTU have developed software for Trials Sequential Analysis  (the TSA software). TSA controls the risks of random errors due to sparse data and repetitive analyses of data in cumulative meta-analyses. Cochrane authors are encouraged to use TSA in their reviews in order to assess the robustness of data in review meta-analyses (Jakobsen JC et al. 2014).

All mentioned software is regularly updated and its functionalities improved.

The Nordic Cochrane Centre is an independent research organisation, part of Cochrane, with main responsibilities of training review authors from the Nordic region.